Case report a 77 yearold female presented with a oneyear long history of progressively worsening headaches, alongwith a 3. Once you merge pdfs, you can send them directly to your email or download the file to our computer and view. Pdf chordomas are rare tumors that can develop anywhere along the craniospinal axis. Chordomas are rare tumours of the bone arising along the spine from clivus to sacrum.
The sphenoid sinus and upper clivus are then exposed for tumor removal. Chordoma is a rare neoplasm considered to be of low to intermediate malignancy and originating from the notochord cells. Intradural extraosseous chordoma has clearly different features from those of typical chordoma it is uncommon, occurs almost exclusively in the prepontine and clival regions, and is encountered in 0. For more inferior lesions, we have modified the transoraltranspharyngeal approach by. Chordoma chondrosarcoma clivus abducens nerve proton beam therapy brachyury. Once files have been uploaded to our system, change the order of your pdf documents. Chordoma, a rare bone tumor that occurs along the spine, has led scientists on a fascinating. Transcranial approaches to clival chordomas provide a circuitous route to the site of origin of the tumor often involving extensive bone drilling and.
Pdf merge combinejoin pdf files online for free soda pdf. Get a printable copy pdf file of the complete article 1. Dpt case presentation schedule 2019 university of iowa. The clival chordoma and chondrosarcoma are the most common of these tumors.
Metastatic disease to the clivus mimicking clival chordomas. Expert recommendations for the diagnosis and treatment of. Rearrange individual pages or entire files in the desired order. Hoxa7, hoxa9, and hoxa10 are differentially expressed in. The authors describe a case of a giant clivus chordoma in a 42yearold male presenting with symptoms due to compression of the brain stem and hypothalamus, including the unusual manifestation of pathological laughter. Characterization of clivus chordoma tumor cell line mugcc1. Pilar merino, md, phd, gema franco, md, and rosario gomez. Establishment of clival chordoma cell line mugcc1 and. Endoscopic endonasal transclival resection of chordomas. All authors read and approved the final manuscript. Chordomas are rare, malignant bone tumors of the skullbase and axial skeleton. Best practices for the management of localregional recurrent.
Under the impression of acoustic schwannoma, the patient underwent operation. Ks was the major contributor in writing the manuscript. We compared three chordoma cell lines of the clivus region including the. Skull base approaches to clival chordomas request pdf. He was treated by an endoscopic transphenoidal approach.
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